Description: Haploidentical refers to a transplant or graft derived from a donor who is a haploidentical match. This means that the donor and recipient share approximately 50% of their genetic material, which is sufficient for the graft to be accepted by the recipient’s immune system, even though it is not a complete match. This type of transplant is particularly relevant in the context of regenerative medicine and cell therapy, where minimizing the risk of graft rejection is crucial. Haploidentical transplants are commonly used in bone marrow and stem cell transplants, where genetic compatibility is essential for the success of the procedure. The ability to use haploidentical donors significantly expands the number of potential donors available, which is vital in situations where fully compatible donors are scarce. This approach has revolutionized the way transplants are performed, allowing more patients to access treatments that were previously considered impossible due to a lack of suitable genetic matches.
