Description: The term ‘nauseant’ refers to any substance that induces the sensation of nausea, a discomfort that can lead a person to vomit. This phenomenon is a physiological response of the body to certain stimuli, which can be chemical, physical, or emotional. Nauseant substances can act on the central nervous system, affecting the body’s balance and perception. In pharmacology, these substances are studied to understand their mechanisms of action and their effects on the organism. Nausea is a common symptom in various medical conditions and can be induced by medications, toxins, infections, or gastrointestinal disorders. Identifying nauseant substances is crucial in the development of treatments and in assessing the safety of drugs, as the onset of nausea can limit patient adherence to a treatment. Additionally, the study of these substances is also related to the research of antiemetic drugs, which are used to prevent or treat nausea and vomiting. In summary, the term ‘nauseant’ encompasses a wide spectrum of substances and effects, being an area of interest in both pharmacology and general medicine.