Description: Equivalence Tests are a statistical method used to determine whether two treatments or interventions have similar effects in a specific context. This approach is fundamental in clinical research and comparative studies, where the goal is to establish whether a new treatment is as effective as a standard treatment or a placebo. Equivalence tests are based on the idea that, rather than demonstrating that one treatment is superior to another, the aim is to show that the difference between treatments is small enough to consider them equivalent. This translates into the formulation of null and alternative hypotheses that reflect this equivalence, using confidence intervals and equivalence margins to evaluate results. The importance of these tests lies in their ability to provide solid evidence in clinical decision-making and in the regulation of new treatments, ensuring that patients receive therapeutic options that are effective and safe. In summary, Equivalence Tests are an essential tool in applied statistics, especially in the health field, where the comparison of treatments can significantly impact patients’ quality of life.