Description: Lymphopenia is a medical condition characterized by a decrease in the number of lymphocytes in the blood. Lymphocytes are a type of white blood cell that plays a crucial role in the immune system, helping to fight infections and diseases. Lymphopenia can be an indicator of various underlying conditions, including viral infections, autoimmune diseases, and certain types of cancer. This decrease in lymphocytes can affect the body’s ability to respond adequately to pathogens, leading to an increased risk of infections. Lymphopenia is generally classified into three grades: mild, moderate, and severe, depending on the number of lymphocytes present in the blood. The evaluation of lymphopenia is performed through a complete blood count, which allows for counting the number of lymphocytes and determining their proportion in relation to other types of blood cells. It is important to note that lymphopenia is not a disease in itself but a symptom that can be associated with various pathologies. Its diagnosis and treatment require a comprehensive approach, considering the underlying cause and the overall health of the patient.