Description: Uptake inhibitors are substances that prevent the uptake of specific molecules by cells, thus affecting communication and signal transport in the organism. These compounds can act on various metabolic pathways and are fundamental in the study of cellular and molecular biology. Their mechanism of action is based on competition with the molecules that would normally be absorbed by the cells, which can alter physiological and biochemical processes. Uptake inhibitors are of great interest in biomedical research, as they allow for a better understanding of how cells interact with their environment and how internal processes are regulated. Furthermore, their study has led to the development of innovative therapies for the treatment of various diseases, including neurological and psychiatric disorders. In the field of bioinformatics, the analysis of these inhibitors is carried out through computational models that predict their interaction with proteins and other biomolecules, facilitating the design of new drugs and the optimization of existing treatments.